Dr. Maria Duca

CNRS Research Scientist

Director of TNA research group

Institute of Chemistry of Nice (ICN)

UMR7272 Université Côte d'Azur - CNRS

28 avenue Valrose 06100 Nice FRANCE

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Curriculum vitae

  • "Habilitation à Diriger des Recherches" (2012) from University of Nice Sophia Antipolis (now Université Côte d'Azur), Nice, France
  • PhD in Molécular Biochemistry (2005) from Muséum National d'Histoire Naturelle (MNHN), Paris, France
  • "Laurea" in Chemistry and Pharmaceutical Technology (2001) from the Faculty of Pharmacy - University of Bologna, Italy

Academic Responsibilities

Awards and Honours

  • Alexandre Joël Award from Fondation ARC (2004)
  • Michel Delalande Award from the French Pharmacy Academy (2007)

Key Publications

Di Giorgio A., Duca M.* New Chemical Modalities Enabling Specific RNA Targeting and Degradation: Application to SARS-CoV-2 RNA. ACS Cent. Sci. 2020 6, 1647

Joly J.P., Gaysinski M., Zara L., Duca M.*, Benhida, R. Functionalized C-nucleosides as remarkable RNA binders: targeting of prokaryotic ribosomal A-site RNA. Chem. Commun. 2019 27, 10432

Staedel, C., Tran, T.P.A., Giraud, J., Darfeuille, F., Di Giorgio, A., Tourasse, N.J., Salin, F., Uriac, P., Duca, M.* Modulation of oncogenic miRNA biogenesis using functionalized polyamines. Scientific Reports 2018 8, 1667

Vo D.D., Staedel C., Zehnacker L., Benhida R., Darfeuille F., Duca M.* Targeting the production of oncogenic microRNAs with multimodal synthetic small molecules. ACS Chem. Biol. 2014 9, 711.

Duca, M., Trindle, C.O., Hecht, S.M. Structural basis for the exceptional stability of bisaminoacylated nucleotides and transfer RNAs. J. Am. Chem. Soc. 2011, 133, 11368.

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